Engagement of CD11b and CD11c beta2 integrin by antibodies or soluble CD23 induces IL-1beta production on primary human monocytes through mitogen-activated protein kinase-dependent pathways. [electronic resource]
Producer: 20000810Description: 3868-77 p. digitalISSN:- 0006-4971
- Antibodies, Monoclonal -- pharmacology
- Cells, Cultured
- Gene Expression Regulation -- immunology
- Humans
- Integrin alphaXbeta2 -- blood
- Interleukin-1 -- blood
- Macrophage-1 Antigen -- blood
- Mitogen-Activated Protein Kinase 1 -- metabolism
- Mitogen-Activated Protein Kinase 3
- Mitogen-Activated Protein Kinases -- metabolism
- Monocytes -- immunology
- Receptors, IgE -- immunology
- Recombinant Fusion Proteins -- pharmacology
- Transcription, Genetic -- drug effects
- p38 Mitogen-Activated Protein Kinases
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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