Megakaryocyte-targeted synthesis of the integrin beta(3)-subunit results in the phenotypic correction of Glanzmann thrombasthenia. [electronic resource]
Producer: 20000810Description: 3645-51 p. digitalISSN:- 0006-4971
- Antigens, CD -- genetics
- Antigens, CD34 -- blood
- Cell Line
- Cells, Cultured
- Fibrin -- metabolism
- Flow Cytometry
- Genetic Therapy
- Humans
- Integrin beta3
- Integrins -- genetics
- Megakaryocytes -- physiology
- Phenotype
- Platelet Membrane Glycoproteins -- genetics
- Polymerase Chain Reaction
- Recombinant Proteins -- metabolism
- Signal Transduction
- Thrombasthenia -- blood
- Transfection
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.
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