Long-term rAAV-mediated gene transfer of GDNF in the rat Parkinson's model: intrastriatal but not intranigral transduction promotes functional regeneration in the lesioned nigrostriatal system. [electronic resource]
Producer: 20000630Description: 4686-700 p. digitalISSN:- 0270-6474
- Animals
- Benzazepines -- pharmacology
- Corpus Striatum -- drug effects
- Dependovirus
- Dopamine Agonists -- pharmacology
- Female
- Gene Transfer Techniques
- Genes, Reporter
- Genetic Therapy
- Genetic Vectors
- Glial Cell Line-Derived Neurotrophic Factor
- Green Fluorescent Proteins
- Luminescent Proteins -- analysis
- Nerve Growth Factors
- Nerve Regeneration -- physiology
- Nerve Tissue Proteins -- genetics
- Neuroprotective Agents
- Oxidopamine -- toxicity
- Parkinsonian Disorders -- physiopathology
- Rats
- Rats, Sprague-Dawley
- Signal Transduction
- Substantia Nigra -- drug effects
- Tyrosine 3-Monooxygenase -- analysis
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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