Missense mutations interfere with VEGFR-3 signalling in primary lymphoedema. [electronic resource]
Producer: 20000629Description: 153-9 p. digitalISSN:- 1061-4036
- Alleles
- Animals
- Cell Line
- Chromosomes, Human, Pair 5 -- genetics
- Endothelial Growth Factors -- pharmacology
- Enzyme Stability
- Female
- Genes, Dominant -- genetics
- Half-Life
- Humans
- Infant
- Infant, Newborn
- Lymphedema -- congenital
- Male
- Mice
- Models, Molecular
- Molecular Sequence Data
- Mutation, Missense -- genetics
- Pedigree
- Phosphorylation -- drug effects
- Protein Structure, Secondary
- Receptor Protein-Tyrosine Kinases -- chemistry
- Receptors, Cell Surface -- chemistry
- Recombinant Fusion Proteins -- chemistry
- Signal Transduction -- drug effects
- Transcriptional Activation -- drug effects
- Vascular Endothelial Growth Factor C
- Vascular Endothelial Growth Factor Receptor-3
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.
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