High-affinity binding to the GM-CSF receptor requires intact N-glycosylation sites in the extracellular domain of the beta subunit. [electronic resource]
Producer: 20000629Description: 3357-62 p. digitalISSN:- 0006-4971
- Alanine
- Amino Acid Substitution
- Animals
- Asparagine
- Aspartic Acid
- Binding Sites
- COS Cells
- Cell Membrane -- metabolism
- Cloning, Molecular
- Glycosylation
- Granulocyte-Macrophage Colony-Stimulating Factor -- metabolism
- Humans
- Kinetics
- Macromolecular Substances
- Mutagenesis, Site-Directed
- Receptors, Granulocyte-Macrophage Colony-Stimulating Factor -- chemistry
- Recombinant Proteins -- chemistry
- Transfection
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.
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