High frequency of hypermethylation at the 14-3-3 sigma locus leads to gene silencing in breast cancer. [electronic resource]
Producer: 20000630Description: 6049-54 p. digitalISSN:- 0027-8424
- 14-3-3 Proteins
- Azacitidine -- analogs & derivatives
- Breast -- cytology
- Breast Neoplasms -- genetics
- Cell Cycle Proteins -- biosynthesis
- Cell Line -- drug effects
- Cell Line, Transformed -- drug effects
- Cell Transformation, Neoplastic -- genetics
- CpG Islands
- DNA Methylation -- drug effects
- DNA Repair -- genetics
- Decitabine
- Epithelial Cells -- metabolism
- Female
- G2 Phase -- genetics
- Gene Expression Regulation, Neoplastic -- drug effects
- Gene Silencing
- Humans
- Neoplasm Proteins -- biosynthesis
- Protein Biosynthesis
- Proteins -- genetics
- RNA, Messenger -- biosynthesis
- RNA, Neoplasm -- biosynthesis
- Radiation Tolerance -- genetics
- Recombinant Fusion Proteins -- physiology
- Transcription, Genetic
- Transfection
- Tumor Cells, Cultured -- metabolism
- Tyrosine 3-Monooxygenase
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.; Research Support, U.S. Gov't, P.H.S.
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