Ski acts as a co-repressor with Smad2 and Smad3 to regulate the response to type beta transforming growth factor. [electronic resource]
Producer: 20000630Description: 5924-9 p. digitalISSN:- 0027-8424
- Cell Nucleus -- chemistry
- DNA-Binding Proteins -- antagonists & inhibitors
- Female
- Gene Expression Regulation -- drug effects
- Gene Expression Regulation, Neoplastic -- drug effects
- Genes, Reporter
- Humans
- Luciferases -- biosynthesis
- Macromolecular Substances
- Melanoma -- pathology
- Neoplasm Proteins -- physiology
- Promoter Regions, Genetic
- Proto-Oncogene Proteins -- physiology
- Recombinant Fusion Proteins -- biosynthesis
- Repressor Proteins -- physiology
- Smad2 Protein
- Smad3 Protein
- Trans-Activators -- antagonists & inhibitors
- Transcription Factors -- physiology
- Transcription, Genetic -- drug effects
- Transforming Growth Factor beta -- antagonists & inhibitors
- Two-Hybrid System Techniques
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.
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