Proteasome inhibition circumvents solid tumor resistance to topoisomerase II-directed drugs. [electronic resource]
Producer: 20000601Description: 2429-34 p. digitalISSN:- 0008-5472
- Acetylcysteine -- analogs & derivatives
- Animals
- Antigens, Neoplasm
- Antineoplastic Agents -- pharmacology
- Antineoplastic Agents, Phytogenic -- pharmacology
- Blotting, Northern
- Cell Cycle -- drug effects
- Cysteine Endopeptidases -- metabolism
- Cysteine Proteinase Inhibitors -- pharmacology
- DNA Topoisomerases, Type II -- biosynthesis
- DNA-Binding Proteins
- Dose-Response Relationship, Drug
- Doxorubicin -- pharmacology
- Etoposide -- pharmacology
- Glucose -- metabolism
- Humans
- Hypoxia
- Immunoblotting
- Isoenzymes -- antagonists & inhibitors
- Methotrexate -- pharmacology
- Mice
- Mice, Nude
- Multienzyme Complexes -- metabolism
- Neoplasm Transplantation
- Nucleic Acid Synthesis Inhibitors -- pharmacology
- Proteasome Endopeptidase Complex
- Time Factors
- Topoisomerase II Inhibitors
- Tumor Cells, Cultured
- Vincristine -- pharmacology
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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