The radiosensitizing agent 7-hydroxystaurosporine (UCN-01) inhibits the DNA damage checkpoint kinase hChk1. [electronic resource]
Producer: 20000511Description: 2108-12 p. digitalISSN:- 0008-5472
- Alkaloids -- pharmacology
- Antineoplastic Agents -- pharmacology
- Cell Cycle Proteins -- metabolism
- Checkpoint Kinase 1
- Checkpoint Kinase 2
- DNA Damage -- drug effects
- G2 Phase -- drug effects
- Humans
- Inhibitory Concentration 50
- K562 Cells
- Models, Biological
- Phosphorylation -- drug effects
- Phosphoserine -- metabolism
- Protein Kinase Inhibitors
- Protein Kinases -- metabolism
- Protein Serine-Threonine Kinases -- antagonists & inhibitors
- Radiation-Sensitizing Agents -- pharmacology
- Signal Transduction -- drug effects
- Staurosporine -- analogs & derivatives
- cdc25 Phosphatases -- metabolism
No physical items for this record
Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.
There are no comments on this title.
Log in to your account to post a comment.