Degradation of methoxysuccinyl-phe-leu-phe-7-amido-4-trifluoromethyl coumarin (FLF) in cultured myotubes and HepG2 cells is proteasome- and calpain/calcium-dependent. [electronic resource]
Producer: 20000811Description: 677-86 p. digitalISSN:- 1357-2725
- Animals
- Calcium -- metabolism
- Calpain -- metabolism
- Cell Line
- Coumarins -- metabolism
- Cysteine Endopeptidases -- metabolism
- Cysteine Proteinase Inhibitors -- pharmacology
- Humans
- Insulin -- metabolism
- Lactones -- pharmacology
- Lysosomes -- metabolism
- Male
- Multienzyme Complexes -- metabolism
- Oligopeptides -- metabolism
- Proteasome Endopeptidase Complex
- Rats
- Rats, Sprague-Dawley
- Tumor Cells, Cultured
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.
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