The leukaemic oncoproteins Bcr-Abl and Tel-Abl (ETV6/Abl) have altered substrate preferences and activate similar intracellular signalling pathways. [electronic resource]
Producer: 20000504Description: 1684-90 p. digitalISSN:- 0950-9232
- 3T3 Cells
- Adaptor Proteins, Signal Transducing
- Amino Acid Sequence
- Animals
- Catalysis
- Cell Line
- Epitopes -- metabolism
- GTP Phosphohydrolases -- metabolism
- Guanosine Triphosphate -- physiology
- Hematopoietic Stem Cells
- Humans
- MAP Kinase Signaling System
- Macromolecular Substances
- Mice
- Molecular Sequence Data
- Nuclear Proteins -- metabolism
- Oncogene Proteins, Fusion -- metabolism
- Peptide Fragments -- chemical synthesis
- Phosphorylation
- Protein Processing, Post-Translational
- Protein Serine-Threonine Kinases
- Proto-Oncogene Proteins -- metabolism
- Proto-Oncogene Proteins c-abl -- metabolism
- Proto-Oncogene Proteins c-akt
- Proto-Oncogene Proteins c-crk
- Proto-Oncogene Proteins p21(ras) -- metabolism
- Substrate Specificity
- Translocation, Genetic
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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