Epidermal growth factor (EGF) suppresses staurosporine-induced apoptosis by inducing mcl-1 via the mitogen-activated protein kinase pathway. [electronic resource]
Producer: 20000504Description: 1665-75 p. digitalISSN:- 0950-9232
- Androstadienes -- pharmacology
- Apoptosis -- drug effects
- Carcinoma -- genetics
- Cysteine Endopeptidases -- physiology
- Cysteine Proteinase Inhibitors -- pharmacology
- DNA, Antisense -- genetics
- Epidermal Growth Factor -- pharmacology
- ErbB Receptors -- drug effects
- Esophageal Neoplasms -- genetics
- Flavonoids -- pharmacology
- Gene Expression Regulation, Neoplastic -- drug effects
- Humans
- MAP Kinase Kinase Kinase 1
- MAP Kinase Signaling System -- drug effects
- Mitogen-Activated Protein Kinase 1 -- genetics
- Mitogen-Activated Protein Kinase 3
- Mitogen-Activated Protein Kinases -- physiology
- Myeloid Cell Leukemia Sequence 1 Protein
- Neoplasm Proteins -- biosynthesis
- Phosphoinositide-3 Kinase Inhibitors
- Protein Serine-Threonine Kinases -- physiology
- Proto-Oncogene Proteins c-bcl-2
- Proto-Oncogene Proteins c-raf -- physiology
- Recombinant Fusion Proteins -- physiology
- Staurosporine -- antagonists & inhibitors
- Transfection
- Tumor Cells, Cultured -- drug effects
- Wortmannin
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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