Monoclonal antibody screening of a phage-displayed random peptide library reveals mimotopes of chemokine receptor CCR5: implications for the tertiary structure of the receptor and for an N-terminal binding site for HIV-1 gp120. [electronic resource]
Producer: 20000525Description: 1162-71 p. digitalISSN:- 0014-2980
- Amino Acid Sequence
- Animals
- Antibodies, Monoclonal -- immunology
- Antibody Affinity
- Antibody Specificity
- B-Lymphocytes
- Binding, Competitive
- Cloning, Molecular
- Enzyme-Linked Immunosorbent Assay
- Epitopes -- chemistry
- HIV Envelope Protein gp120 -- metabolism
- Mice
- Models, Molecular
- Molecular Mimicry
- Peptide Library
- Peptides -- chemical synthesis
- Protein Binding
- Protein Structure, Tertiary
- Receptors, CCR5 -- chemistry
- Sequence Analysis, Protein
- Tumor Cells, Cultured
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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