The contribution of hepatic inactivation of testosterone to the lowering of serum testosterone levels by ketoconazole. [electronic resource]
Producer: 20000602Description: 128-37 p. digitalISSN:- 1096-6080
- Animals
- Antifungal Agents -- pharmacology
- Aryl Hydrocarbon Hydroxylases
- Biotransformation
- Cytochrome P-450 Enzyme Inhibitors
- Cytochrome P-450 Enzyme System -- metabolism
- Cytosol -- drug effects
- Electrophoresis, Polyacrylamide Gel
- Glucuronosyltransferase -- metabolism
- Immunoblotting
- Ketoconazole -- pharmacology
- Liver -- drug effects
- Male
- Mice
- Microsomes, Liver -- drug effects
- Steroid Hydroxylases -- antagonists & inhibitors
- Sulfotransferases -- metabolism
- Testis -- drug effects
- Testosterone -- blood
- Time Factors
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Publication Type: Journal Article; Research Support, U.S. Gov't, Non-P.H.S.
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