Selective cytotoxic activity of a novel ribonucleoside diphosphate reductase inhibitor MDL-101,731 against thyroid cancer in vitro. [electronic resource]
Producer: 20000414Description: 185-91 p. digitalISSN:- 0015-5500
- Antineoplastic Agents -- pharmacology
- Apoptosis -- drug effects
- Carcinoma -- pathology
- Carcinoma, Papillary -- pathology
- Cell Survival -- drug effects
- DNA Replication -- drug effects
- DNA, Neoplasm -- biosynthesis
- Deoxycytidine -- analogs & derivatives
- Doxorubicin -- pharmacology
- Drug Screening Assays, Antitumor
- Enzyme Inhibitors -- pharmacology
- Fibroblasts -- drug effects
- Flow Cytometry
- Humans
- Methotrexate -- pharmacology
- Neoplasm Proteins -- antagonists & inhibitors
- Proto-Oncogene Proteins c-bcl-2 -- biosynthesis
- Ribonucleoside Diphosphate Reductase -- antagonists & inhibitors
- Thyroid Neoplasms -- pathology
- Tumor Cells, Cultured -- drug effects
- Vincristine -- pharmacology
- fas Receptor -- biosynthesis
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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