Redirected perforin-dependent lysis of colon carcinoma by ex vivo genetically engineered CTL. [electronic resource]
Producer: 20000504Description: 3705-12 p. digitalISSN:- 0022-1767
- Adenocarcinoma -- genetics
- Adoptive Transfer
- Animals
- Binding Sites -- genetics
- Carcinoembryonic Antigen -- metabolism
- Carrier Proteins -- genetics
- Cell Division -- immunology
- Colonic Neoplasms -- genetics
- Cytokines -- metabolism
- Cytotoxicity, Immunologic -- genetics
- Epitopes, T-Lymphocyte -- immunology
- Humans
- Immunoglobulin Fragments -- biosynthesis
- Immunoglobulin Variable Region -- genetics
- Interferon-gamma -- physiology
- Lymphocyte Count
- Membrane Glycoproteins -- genetics
- Mice
- Mice, Inbred BALB C
- Mice, Inbred C57BL
- Mice, Knockout
- Mice, SCID
- Neoplasm Transplantation
- Perforin
- Pore Forming Cytotoxic Proteins
- Receptors, Cell Surface
- Recombinant Fusion Proteins -- biosynthesis
- T-Lymphocytes, Cytotoxic -- immunology
- Transduction, Genetic
- Tumor Cells, Cultured
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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