The salicylate metabolite gentisic acid, but not the parent drug, inhibits glucose autoxidation-mediated atherogenic modification of low density lipoprotein. [electronic resource]
Producer: 20000503Description: 47-50 p. digitalISSN:- 0014-5793
- Arteriosclerosis -- prevention & control
- Aspirin -- metabolism
- Cells, Cultured
- Diabetic Angiopathies -- prevention & control
- Endothelium, Vascular -- drug effects
- Gentisates
- Glucose -- metabolism
- Humans
- Hydroxybenzoates -- metabolism
- Iron Chelating Agents -- metabolism
- Lipoproteins, LDL -- metabolism
- Male
- Oxidation-Reduction
- Prodrugs -- metabolism
- Reactive Oxygen Species -- metabolism
- Salicylic Acid -- metabolism
- Thromboplastin -- biosynthesis
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Publication Type: Journal Article
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