A mutant herpes simplex virus type 1 thymidine kinase reporter gene shows improved sensitivity for imaging reporter gene expression with positron emission tomography. [electronic resource]
Producer: 20000425Description: 2785-90 p. digitalISSN:- 0027-8424
- Acyclovir -- metabolism
- Adenoviridae -- metabolism
- Animals
- Antiviral Agents -- metabolism
- Blotting, Northern
- Blotting, Western
- Chromatography, High Pressure Liquid
- Escherichia coli -- metabolism
- Fluorine -- pharmacokinetics
- Ganciclovir -- metabolism
- Genes, Reporter
- Herpesvirus 1, Human -- enzymology
- Liver -- metabolism
- Mice
- Mutagenesis
- Prodrugs -- metabolism
- Rats
- Thymidine Kinase -- genetics
- Time Factors
- Tomography, Emission-Computed -- methods
- Transfection
- Tumor Cells, Cultured
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.; Research Support, U.S. Gov't, P.H.S.
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