In vivo uptake of radiolabeled MDA2, an oxidation-specific monoclonal antibody, provides an accurate measure of atherosclerotic lesions rich in oxidized LDL and is highly sensitive to their regression. [electronic resource]
Producer: 20000518Description: 689-97 p. digitalISSN:- 1079-5642
- Animals
- Antibodies, Monoclonal -- pharmacokinetics
- Antibody Specificity
- Aorta, Thoracic -- metabolism
- Arteriosclerosis -- diagnosis
- Cholesterol -- blood
- Diet, Atherogenic
- Epitopes -- metabolism
- Hyperlipidemias -- diagnosis
- Iodine Radioisotopes -- pharmacokinetics
- Lipoproteins, LDL -- analysis
- Malondialdehyde -- immunology
- Mice
- Mice, Knockout
- Organ Size
- Oxidation-Reduction
- Rabbits
- Receptors, LDL -- genetics
- Staining and Labeling
- Triglycerides -- blood
- Vitamin E -- blood
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.
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