Heterogeneous apoptotic responses of prostate cancer cell lines identify an association between sensitivity to staurosporine-induced apoptosis, expression of Bcl-2 family members, and caspase activation. [electronic resource]
Producer: 20000314Description: 260-73 p. digitalISSN:- 0270-4137
- Apoptosis -- drug effects
- Apoptosis Regulatory Proteins
- Biological Transport
- Caspase 3
- Caspase 7
- Caspases -- metabolism
- Catalysis
- Cell Survival
- Cytochrome c Group -- metabolism
- Cytosol -- metabolism
- DNA Fragmentation
- Enzyme Activation
- Enzyme Inhibitors -- pharmacology
- Humans
- In Situ Nick-End Labeling
- Intracellular Membranes -- physiology
- Male
- Mitochondria -- physiology
- Necrosis
- Poly(ADP-ribose) Polymerases -- metabolism
- Prostatic Neoplasms -- enzymology
- Proteins -- metabolism
- Proto-Oncogene Proteins -- biosynthesis
- Proto-Oncogene Proteins c-bcl-2 -- biosynthesis
- Staurosporine -- pharmacology
- Topoisomerase II Inhibitors
- Tumor Cells, Cultured
- bcl-2-Associated X Protein
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
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