DNA sequence context modulates the impact of a cisplatin 1,2-d(GpG) intrastrand cross-link on the conformational and thermodynamic properties of duplex DNA. [electronic resource]
Producer: 20000317Description: 803-12 p. digitalISSN:- 0022-2836
- Base Pairing -- genetics
- Base Sequence
- Calorimetry, Differential Scanning
- Circular Dichroism
- Cisplatin -- metabolism
- Cross-Linking Reagents -- metabolism
- DNA -- chemistry
- DNA Adducts -- chemistry
- DNA-Binding Proteins -- metabolism
- High Mobility Group Proteins -- metabolism
- Nucleic Acid Conformation -- radiation effects
- Nucleic Acid Denaturation -- radiation effects
- Oligodeoxyribonucleotides -- chemistry
- Substrate Specificity
- Temperature
- Thermodynamics
- Ultraviolet Rays
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.
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