The first alpha helix of interleukin (IL)-2 folds as a homotetramer, acts as an agonist of the IL-2 receptor beta chain, and induces lymphokine-activated killer cells. [electronic resource]
Producer: 20000418Description: 529-40 p. digitalISSN:- 0022-1007
- Amino Acid Sequence
- Animals
- Binding Sites
- CD8-Positive T-Lymphocytes -- metabolism
- Cell Line
- Enzyme Activation -- drug effects
- Humans
- Interferon-gamma -- analysis
- Interleukin-2 -- chemistry
- Killer Cells, Lymphokine-Activated -- metabolism
- Lymphocyte Activation -- drug effects
- Lymphocyte Specific Protein Tyrosine Kinase p56(lck) -- metabolism
- Lymphocyte Subsets -- metabolism
- Mice
- Molecular Sequence Data
- Monocytes -- drug effects
- Peptide Fragments -- chemistry
- Protein Folding
- Receptors, Interleukin-2 -- agonists
- Signal Transduction
- src Homology Domains
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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