Activation of the heterodimeric IkappaB kinase alpha (IKKalpha)-IKKbeta complex is directional: IKKalpha regulates IKKbeta under both basal and stimulated conditions. [electronic resource]
Producer: 20000215Description: 1170-8 p. digitalISSN:- 0270-7306
- Cell Line
- Dimerization
- Enzyme Activation
- Gene Products, tax -- pharmacology
- HeLa Cells
- Humans
- I-kappa B Kinase
- MAP Kinase Kinase Kinase 1
- MAP Kinase Kinase Kinases -- metabolism
- Mutation
- Phosphorylation
- Protein Serine-Threonine Kinases -- chemistry
- Protein Structure, Quaternary
- Proto-Oncogene Proteins -- metabolism
- Recombinant Proteins -- chemistry
- Signal Transduction
- Tumor Necrosis Factor-alpha -- pharmacology
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.
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