Double suicide gene therapy augments the antitumor activity of a replication-competent lytic adenovirus through enhanced cytotoxicity and radiosensitization. [electronic resource]
Producer: 20000211Description: 67-76 p. digitalISSN:- 1043-0342
- Adenoviridae -- enzymology
- Animals
- Artificial Gene Fusion
- Cell Survival
- Combined Modality Therapy
- Cytosine Deaminase
- Female
- Genetic Therapy
- Genetic Vectors
- Herpesvirus 1, Human -- enzymology
- Injections, Intralesional
- Mice
- Mice, Nude
- Neoplasm Transplantation
- Neoplasms, Experimental -- radiotherapy
- Nucleoside Deaminases -- genetics
- Radiation Tolerance
- Thymidine Kinase -- genetics
- Virus Replication
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Publication Type: Journal Article; Research Support, U.S. Gov't, P.H.S.
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