Degradation of heterotrimeric Galpha(o) subunits via the proteosome pathway is induced by the hsp90-specific compound geldanamycin. [electronic resource]
Producer: 20000224Description: 1565-9 p. digitalISSN:- 0021-9258
- Animals
- Benzoquinones
- COS Cells
- Cell Line
- Cysteine Endopeptidases -- metabolism
- Dose-Response Relationship, Drug
- Enzyme Inhibitors -- metabolism
- GTP-Binding Proteins -- metabolism
- HSP90 Heat-Shock Proteins -- metabolism
- Lactams, Macrocyclic
- Multienzyme Complexes -- metabolism
- PC12 Cells
- Precipitin Tests
- Proteasome Endopeptidase Complex
- Quinones -- metabolism
- Rats
- Time Factors
- Transfection
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Publication Type: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.
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