The p16 status of tumor cell lines identifies small molecule inhibitors specific for cyclin-dependent kinase 4. [electronic resource]
Producer: 20000214Description: 4279-86 p. digitalISSN:- 1078-0432
- Antineoplastic Agents -- pharmacology
- Cyclin-Dependent Kinase 4
- Cyclin-Dependent Kinase Inhibitor p16 -- deficiency
- Cyclin-Dependent Kinases -- antagonists & inhibitors
- Drug Screening Assays, Antitumor
- Enzyme Inhibitors -- pharmacology
- Genes, p16
- Growth Inhibitors -- pharmacology
- Humans
- Polymerase Chain Reaction
- Polymorphism, Single-Stranded Conformational
- Proto-Oncogene Proteins
- Structure-Activity Relationship
- Substrate Specificity
- Tumor Cells, Cultured
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Publication Type: Comparative Study; Journal Article; Research Support, U.S. Gov't, P.H.S.
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