Rac1 and Cdc42 are required for phagocytosis, but not NF-kappaB-dependent gene expression, in macrophages challenged with Pseudomonas aeruginosa. [electronic resource]
Producer: 20000131Description: 141-6 p. digitalISSN:- 0021-9258
- Animals
- Biological Transport
- Cell Compartmentation
- Cell Nucleus
- Cells, Cultured
- Chimerin 1 -- genetics
- Cyclooxygenase 2
- Fimbriae Proteins
- Flagellin
- Gene Expression
- Guanosine Triphosphate -- metabolism
- Inflammation Mediators -- metabolism
- Isoenzymes -- biosynthesis
- Macrophages -- microbiology
- Membrane Proteins
- Mice
- Mutation
- NF-kappa B -- metabolism
- Nitric Oxide Synthase -- biosynthesis
- Nitric Oxide Synthase Type II
- Phagocytosis
- Prostaglandin-Endoperoxide Synthases -- biosynthesis
- Pseudomonas aeruginosa -- pathogenicity
- Signal Transduction
- Tumor Necrosis Factor-alpha -- biosynthesis
- cdc42 GTP-Binding Protein -- genetics
- rac1 GTP-Binding Protein -- genetics
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.
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