In vitro and in vivo characterization of conantokin-R, a selective NMDA receptor antagonist isolated from the venom of the fish-hunting snail Conus radiatus. [electronic resource]
Producer: 20000127Description: 425-32 p. digitalISSN:- 0022-3565
- Animals
- Anticonvulsants -- therapeutic use
- Behavior, Animal -- drug effects
- Binding, Competitive
- Cerebral Cortex -- drug effects
- Conotoxins -- chemical synthesis
- Dizocilpine Maleate -- therapeutic use
- Dose-Response Relationship, Drug
- Drug Interactions
- Electroshock
- Evoked Potentials -- drug effects
- Female
- Glutamic Acid -- pharmacology
- In Vitro Techniques
- Kainic Acid -- pharmacology
- Male
- Mice
- Mollusk Venoms -- chemistry
- Oocytes -- physiology
- Pentylenetetrazole -- toxicity
- Piperidines -- therapeutic use
- Receptors, AMPA -- classification
- Receptors, N-Methyl-D-Aspartate -- antagonists & inhibitors
- Recombinant Proteins
- Seizures -- drug therapy
- Sound -- adverse effects
- Xenopus -- physiology
- gamma-Aminobutyric Acid -- pharmacology
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Publication Type: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.
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