Oxygenated analogues of 1-[2-(Diphenylmethoxy)ethyl]- and 1-[2-[Bis(4-fluorophenyl)methoxy]ethyl]-4-(3-phenylpropyl)piperazines (GBR 12935 and GBR 12909) as potential extended-action cocaine-abuse therapeutic agents. [electronic resource]
Producer: 20000104Description: 5029-42 p. digitalISSN:- 0022-2623
- Animals
- Carrier Proteins -- metabolism
- Cocaine-Related Disorders -- drug therapy
- Delayed-Action Preparations
- Dopamine -- metabolism
- Dopamine Plasma Membrane Transport Proteins
- Dopamine Uptake Inhibitors -- chemical synthesis
- Hydroxylation
- Ligands
- Macaca mulatta
- Male
- Membrane Glycoproteins
- Membrane Transport Proteins
- Methylation
- Molecular Structure
- Nerve Tissue Proteins
- Oxygen -- chemistry
- Piperazines -- chemical synthesis
- Rats
- Structure-Activity Relationship
- Tritium
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Publication Type: Journal Article; Research Support, U.S. Gov't, P.H.S.
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