Characterization of the P140K, PVP(138-140)MLK, and G156A O6-methylguanine-DNA methyltransferase mutants: implications for drug resistance gene therapy. [electronic resource]
Producer: 19991214Description: 2769-78 p. digitalISSN:- 1043-0342
- Antineoplastic Agents -- pharmacology
- Carmustine -- pharmacology
- Cell Survival -- drug effects
- Cloning, Molecular
- Drug Interactions
- Drug Resistance, Multiple -- genetics
- Drug Resistance, Neoplasm
- Enzyme Stability
- Gene Expression
- Genetic Therapy
- Guanine -- analogs & derivatives
- Humans
- K562 Cells
- Mutation
- O(6)-Methylguanine-DNA Methyltransferase -- genetics
- Transfection
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Publication Type: Journal Article; Research Support, U.S. Gov't, P.H.S.
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