Cell shrinkage triggers the activation of mitogen-activated protein kinases by hypertonicity in the rat kidney medullary thick ascending limb of the Henle's loop. Requirement of p38 kinase for the regulatory volume increase response. [electronic resource]
Producer: 19991229Description: 34103-10 p. digitalISSN:- 0021-9258
- Animals
- Cell Size -- physiology
- Dose-Response Relationship, Drug
- Enzyme Activation -- drug effects
- Hypertonic Solutions -- pharmacology
- In Vitro Techniques
- Isotonic Solutions -- pharmacology
- Kidney Medulla -- cytology
- Loop of Henle -- cytology
- Male
- Mitogen-Activated Protein Kinases -- metabolism
- Osmolar Concentration
- Phosphorylation -- drug effects
- Rats
- Rats, Wistar
- Sodium Chloride -- pharmacology
- Urea -- pharmacology
- p38 Mitogen-Activated Protein Kinases
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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