Tyr-->Trp-substituted peptide 115-129 of a Lys49 phospholipase A(2) expresses enhanced membrane-damaging activities and reproduces its in vivo myotoxic effect. [electronic resource]
Producer: 19991227Description: 19-26 p. digitalISSN:- 0006-3002
- Amino Acid Sequence
- Animals
- Cells, Cultured
- Creatine Kinase -- blood
- Crotalid Venoms -- chemistry
- Endothelium -- drug effects
- Erythrocytes -- drug effects
- Escherichia coli -- drug effects
- Group II Phospholipases A2
- Immunoenzyme Techniques
- Injections, Intramuscular
- Lysine -- chemistry
- Membranes -- drug effects
- Mice
- Muscle, Skeletal -- drug effects
- Neurotoxins -- chemistry
- Peptide Fragments -- chemistry
- Phospholipases A -- chemistry
- Reptilian Proteins
- Tryptophan -- chemistry
- Tyrosine -- chemistry
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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