Impaired integrin-mediated signal transduction, altered cytoskeletal structure and reduced motility in Hck/Fgr deficient macrophages. [electronic resource]
Producer: 20000128Description: 4067-78 p. digitalISSN:- 0021-9533
- Actins -- metabolism
- Animals
- Antibodies, Monoclonal -- immunology
- Antigens, CD -- chemistry
- Bone Marrow Cells -- cytology
- Caseins -- pharmacology
- Cell Adhesion -- drug effects
- Cell Adhesion Molecules -- metabolism
- Cell Movement -- physiology
- Cells, Cultured
- Cross-Linking Reagents -- pharmacology
- Cytoskeleton -- metabolism
- Enzyme Activation
- Enzyme Precursors -- drug effects
- Extracellular Matrix -- metabolism
- Extracellular Matrix Proteins -- pharmacology
- Fibronectins -- pharmacology
- Focal Adhesion Kinase 2
- Integrin alpha5
- Integrin beta1 -- chemistry
- Integrins -- metabolism
- Intracellular Signaling Peptides and Proteins
- Macrophages -- cytology
- Macrophages, Peritoneal -- cytology
- Mice
- Mice, Knockout
- Phosphorylation -- drug effects
- Protein-Tyrosine Kinases -- deficiency
- Proto-Oncogene Proteins -- deficiency
- Proto-Oncogene Proteins c-hck
- Pseudopodia
- Signal Transduction
- Syk Kinase
- Tyrosine -- metabolism
- src-Family Kinases
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.
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