N(epsilon)-(carboxymethyl)lysine adducts of proteins are ligands for receptor for advanced glycation end products that activate cell signaling pathways and modulate gene expression. [electronic resource]
Producer: 19991216Description: 31740-9 p. digitalISSN:- 0021-9258
- Animals
- Diabetes Mellitus
- Endothelium, Vascular -- cytology
- Gene Expression Regulation
- Glycation End Products, Advanced
- Humans
- Lung -- metabolism
- Lysine -- analogs & derivatives
- Mice
- Mice, Inbred BALB C
- Muscle, Smooth, Vascular -- metabolism
- NF-kappa B -- metabolism
- Phagocytes -- metabolism
- Protein Binding
- Protein Processing, Post-Translational
- Receptor for Advanced Glycation End Products
- Receptors, Immunologic -- metabolism
- Renal Insufficiency
- Serum Albumin -- metabolism
- Signal Transduction
- Vascular Cell Adhesion Molecule-1 -- biosynthesis
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.
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