Cerebral endothelial cells release TNF-alpha after stimulation with cell walls of Streptococcus pneumoniae and regulate inducible nitric oxide synthase and ICAM-1 expression via autocrine loops. [electronic resource]
Producer: 19991104Description: 4308-14 p. digitalISSN:- 0022-1767
- Animals
- Autocrine Communication -- immunology
- Brain -- cytology
- Cell Wall -- immunology
- Cells, Cultured
- Dexamethasone -- pharmacology
- Dose-Response Relationship, Immunologic
- Endothelium, Vascular -- cytology
- Guanidines -- pharmacology
- Immune Sera -- pharmacology
- Intercellular Adhesion Molecule-1 -- biosynthesis
- Kinetics
- Microcirculation -- immunology
- Nitric Oxide -- metabolism
- Nitric Oxide Synthase -- biosynthesis
- Nitric Oxide Synthase Type II
- Nitroarginine -- pharmacology
- RNA, Messenger -- biosynthesis
- Rats
- Rats, Wistar
- Streptococcus pneumoniae -- immunology
- Tumor Necrosis Factor-alpha -- antagonists & inhibitors
- Up-Regulation -- immunology
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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