A defect in interleukin 12-induced activation and interferon gamma secretion of peripheral natural killer T cells in nonobese diabetic mice suggests new pathogenic mechanisms for insulin-dependent diabetes mellitus. [electronic resource]
Producer: 19991104Description: 963-72 p. digitalISSN:- 0022-1007
- Animals
- Autoimmunity
- Cell Differentiation
- Diabetes Mellitus, Type 1 -- genetics
- Inflammation
- Interferon-gamma -- biosynthesis
- Interleukin-12 -- pharmacology
- Killer Cells, Natural -- immunology
- Lymphocyte Activation -- immunology
- Mice
- Mice, Inbred C57BL
- Mice, Inbred NOD
- Mice, SCID
- Phenotype
- Receptors, Antigen, T-Cell -- immunology
- Th2 Cells -- immunology
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.
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