EB-1, a tyrosine kinase signal transduction gene, is transcriptionally activated in the t(1;19) subset of pre-B ALL, which express oncoprotein E2a-Pbx1. [electronic resource]
Producer: 19991013Description: 4920-9 p. digitalISSN:- 0950-9232
- Adenomatous Polyposis Coli Protein
- Amino Acid Sequence
- B-Lymphocytes -- enzymology
- Bone Marrow Cells -- metabolism
- Cell Line
- Cell Transformation, Neoplastic -- genetics
- Cytoskeletal Proteins -- chemistry
- Expressed Sequence Tags
- Fetus -- metabolism
- Gene Expression Regulation, Neoplastic
- Homeodomain Proteins -- genetics
- Humans
- Molecular Sequence Data
- Neoplasm Proteins -- analysis
- Oncogene Proteins, Fusion -- genetics
- Organ Specificity
- Phosphotyrosine -- metabolism
- Precursor B-Cell Lymphoblastic Leukemia-Lymphoma -- enzymology
- Protein-Tyrosine Kinases -- chemistry
- RNA, Messenger -- analysis
- Sequence Homology, Amino Acid
- Signal Transduction
- Stem Cells -- enzymology
- Transcriptional Activation
- Translocation, Genetic -- genetics
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Publication Type: Journal Article; Research Support, U.S. Gov't, P.H.S.
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