Interferon-alpha inhibits proliferation in human T lymphocytes by abrogation of interleukin 2-induced changes in cell cycle-regulatory proteins. [electronic resource]
Producer: 19991026Description: 575-82 p. digitalISSN:- 1044-9523
- Blotting, Northern
- Cell Cycle -- drug effects
- Cell Cycle Proteins -- metabolism
- Cells, Cultured
- Cyclin G
- Cyclin G1
- Cyclin-Dependent Kinase Inhibitor p27
- Cyclin-Dependent Kinases -- metabolism
- Cyclins -- metabolism
- Humans
- Interferon-alpha -- pharmacology
- Interleukin-2 -- pharmacology
- Lymphocyte Activation -- drug effects
- Microtubule-Associated Proteins -- metabolism
- Phytohemagglutinins -- pharmacology
- Protein Processing, Post-Translational -- drug effects
- Proto-Oncogene Proteins c-myc -- biosynthesis
- RNA, Messenger -- metabolism
- T-Lymphocytes -- cytology
- Time Factors
- Tumor Suppressor Proteins
- Up-Regulation -- drug effects
- cdc25 Phosphatases -- biosynthesis
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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