Oxidative metabolism of monensin in rat liver microsomes and interactions with tiamulin and other chemotherapeutic agents: evidence for the involvement of cytochrome P-450 3A subfamily. [electronic resource]
Producer: 19991007Description: 1039-44 p. digitalISSN:- 0090-9556
- Animals
- Antifungal Agents -- metabolism
- Antineoplastic Agents -- pharmacology
- Aryl Hydrocarbon Hydroxylases
- Chromatography, High Pressure Liquid
- Chromatography, Thin Layer
- Cytochrome P-450 CYP3A
- Cytochrome P-450 Enzyme System -- biosynthesis
- Dealkylation
- Diterpenes -- pharmacology
- Drug Interactions
- Enzyme Induction -- drug effects
- In Vitro Techniques
- Kinetics
- Male
- Microsomes, Liver -- metabolism
- Monensin -- metabolism
- Oxidation-Reduction
- Oxidoreductases, N-Demethylating -- biosynthesis
- Rats
- Rats, Wistar
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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