Transdermal nicotine decreases mucosal IL-8 expression but has no effect on mucin gene expression in ulcerative colitis. [electronic resource]
Producer: 19990924Description: 174-81 p. digitalISSN:- 1078-0998
- Administration, Cutaneous
- Adult
- Blotting, Northern
- Colitis, Ulcerative -- drug therapy
- Colon -- metabolism
- Cytokines -- biosynthesis
- Double-Blind Method
- Female
- Gene Expression -- drug effects
- Humans
- Interleukin-8 -- biosynthesis
- Intestinal Mucosa -- metabolism
- Male
- Mucins -- biosynthesis
- Nicotine -- pharmacology
- RNA, Messenger -- analysis
- Reverse Transcriptase Polymerase Chain Reaction
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Publication Type: Clinical Trial; Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't
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