The dermatofibrosarcoma protuberans-associated collagen type Ialpha1/platelet-derived growth factor (PDGF) B-chain fusion gene generates a transforming protein that is processed to functional PDGF-BB. [electronic resource]
Producer: 19990907Description: 3719-23 p. digitalISSN:- 0008-5472
- 3T3 Cells
- Animals
- Antineoplastic Agents -- pharmacology
- Becaplermin
- Benzamides
- Cell Transformation, Neoplastic -- genetics
- Cosmids
- Dermatofibrosarcoma -- genetics
- Enzyme Inhibitors -- pharmacology
- Imatinib Mesylate
- Male
- Mice
- Mice, Inbred BALB C
- Mice, Nude
- Neoplasm Proteins -- antagonists & inhibitors
- Oncogene Proteins, Fusion -- genetics
- Piperazines -- pharmacology
- Platelet-Derived Growth Factor -- biosynthesis
- Proto-Oncogene Proteins c-sis
- Pyrimidines -- pharmacology
- Receptor Protein-Tyrosine Kinases -- antagonists & inhibitors
- Receptor, Platelet-Derived Growth Factor beta
- Receptors, Platelet-Derived Growth Factor -- drug effects
- Skin Neoplasms -- genetics
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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