IkappaBalpha gene transfer is cytotoxic to squamous-cell lung cancer cells and sensitizes them to tumor necrosis factor-alpha-mediated cell death. [electronic resource]
Producer: 19990907Description: 238-45 p. digitalISSN:- 1044-1549
- Adenoviridae -- genetics
- Carcinoma, Squamous Cell -- metabolism
- Cell Death
- Cell Survival
- DNA-Binding Proteins -- genetics
- Dose-Response Relationship, Drug
- Gene Transfer Techniques
- Genetic Vectors
- Humans
- I-kappa B Proteins
- NF-KappaB Inhibitor alpha
- NF-kappa B -- metabolism
- Transduction, Genetic
- Transgenes
- Tumor Cells, Cultured
- Tumor Necrosis Factor-alpha -- metabolism
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.; Research Support, U.S. Gov't, P.H.S.
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