Site-directed mutagenesis and molecular modeling identify a crucial amino acid in specifying the heparin affinity of FGF-1. [electronic resource]
Producer: 19990915Description: 9264-72 p. digitalISSN:- 0006-2960
- Amino Acid Sequence
- Amino Acids -- chemistry
- Animals
- Binding Sites -- genetics
- Cattle
- Cysteic Acid -- metabolism
- Cysteine -- genetics
- Fibroblast Growth Factor 1
- Fibroblast Growth Factor 2 -- chemistry
- Heparin -- chemistry
- Humans
- Iodine Radioisotopes -- metabolism
- Models, Molecular
- Molecular Sequence Data
- Mutagenesis, Site-Directed
- Oxidation-Reduction
- Phenylalanine -- genetics
- Recombinant Fusion Proteins -- chemistry
- Recombinant Proteins -- chemistry
- Serine -- genetics
- Tyrosine -- genetics
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Publication Type: Journal Article; Research Support, U.S. Gov't, P.H.S.
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