PER and TIM inhibit the DNA binding activity of a Drosophila CLOCK-CYC/dBMAL1 heterodimer without disrupting formation of the heterodimer: a basis for circadian transcription. [electronic resource]
Producer: 19990819Description: 5316-25 p. digitalISSN:- 0270-7306
- ARNTL Transcription Factors
- Animals
- Basic Helix-Loop-Helix Transcription Factors
- CLOCK Proteins
- Circadian Rhythm -- genetics
- DNA -- genetics
- Dimerization
- Drosophila Proteins
- Drosophila melanogaster -- genetics
- Enhancer Elements, Genetic
- Feedback
- Gene Expression Regulation
- Genes, Insect
- Helix-Loop-Helix Motifs -- physiology
- Insect Proteins -- biosynthesis
- Multigene Family
- Nuclear Proteins -- biosynthesis
- Period Circadian Proteins
- Protein Multimerization
- RNA, Messenger -- biosynthesis
- Trans-Activators -- chemistry
- Transcription Factors -- antagonists & inhibitors
- Transcription, Genetic
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Publication Type: Journal Article; Research Support, U.S. Gov't, P.H.S.
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