Human immunodeficiency virus type 1 strains R5 and X4 induce different pathogenic effects in hu-PBL-SCID mice, depending on the state of activation/differentiation of human target cells at the time of primary infection. [electronic resource]
Producer: 19990824Description: 6453-9 p. digitalISSN:- 0022-538X
- Animals
- CD4-Positive T-Lymphocytes -- immunology
- Cell Differentiation
- Disease Models, Animal
- HIV Infections -- immunology
- HIV-1 -- isolation & purification
- Humans
- Immunoglobulin M -- immunology
- Lymphocyte Depletion
- Mice
- Mice, SCID
- Receptors, CCR5 -- biosynthesis
- Receptors, CXCR4 -- biosynthesis
- Viral Envelope Proteins -- physiology
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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