High incidence of allelic loss on chromosome 5 and inactivation of p15INK4B and p16INK4A tumor suppressor genes in oxystress-induced renal cell carcinoma of rats. [electronic resource]
Producer: 19990722Description: 3793-7 p. digitalISSN:- 0950-9232
- Animals
- Base Sequence
- Blotting, Southern
- Carcinogens -- toxicity
- Carcinoma, Renal Cell -- chemically induced
- Carrier Proteins -- genetics
- Cell Cycle Proteins
- Chromosomes, Human, Pair 5 -- genetics
- CpG Islands
- Crosses, Genetic
- Cyclin-Dependent Kinase Inhibitor p15
- Cyclin-Dependent Kinase Inhibitor p16
- DNA Methylation
- DNA, Neoplasm -- genetics
- Ferric Compounds -- toxicity
- Gene Deletion
- Genes, Tumor Suppressor
- Genes, p16
- Humans
- Kidney Neoplasms -- chemically induced
- Kidney Tubules, Proximal -- drug effects
- Loss of Heterozygosity
- Microsatellite Repeats
- Molecular Sequence Data
- Nitrilotriacetic Acid -- analogs & derivatives
- Oxidative Stress
- Point Mutation
- Polymerase Chain Reaction
- Polymorphism, Single-Stranded Conformational
- Rats
- Rats, Wistar
- Tumor Suppressor Proteins
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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