Arachidonic acid directly mediates the rapid effects of 24,25-dihydroxyvitamin D3 via protein kinase C and indirectly through prostaglandin production in resting zone chondrocytes. [electronic resource]
Producer: 19990715Description: 2991-3002 p. digitalISSN:- 0013-7227
- 24,25-Dihydroxyvitamin D 3 -- pharmacology
- Animals
- Arachidonic Acid -- metabolism
- Cell Line
- Chondrocytes -- drug effects
- Diglycerides -- pharmacology
- Dose-Response Relationship, Drug
- Drug Synergism
- Male
- Prostaglandins -- biosynthesis
- Protein Kinase C -- physiology
- Rats
- Time Factors
- gamma-Linolenic Acid -- pharmacology
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Publication Type: Journal Article; Research Support, U.S. Gov't, Non-P.H.S.; Research Support, U.S. Gov't, P.H.S.
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