Blocking transforming growth factor beta signaling in transgenic epidermis accelerates chemical carcinogenesis: a mechanism associated with increased angiogenesis. [electronic resource]
Producer: 19990719Description: 2861-8 p. digitalISSN:- 0008-5472
- Animals
- Carcinogens -- toxicity
- Epidermis -- drug effects
- Genes, ras
- Genetic Predisposition to Disease
- Humans
- Mice
- Mice, Transgenic
- Neoplasm Metastasis -- genetics
- Neovascularization, Pathologic
- Papilloma -- blood supply
- Protein Serine-Threonine Kinases
- Receptor, Transforming Growth Factor-beta Type II
- Receptors, Transforming Growth Factor beta -- genetics
- Signal Transduction -- physiology
- Skin Neoplasms -- blood supply
- Transforming Growth Factor beta -- antagonists & inhibitors
- Tumor Suppressor Protein p53 -- genetics
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.
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