Activation of the cAMP signaling pathway increases apoptosis in human B-precursor cells and is associated with downregulation of Mcl-1 expression. [electronic resource]
Producer: 19990617Description: 71-80 p. digitalISSN:- 0021-9541
- 8-Bromo Cyclic Adenosine Monophosphate -- analogs & derivatives
- Adult
- Apoptosis -- drug effects
- B-Lymphocytes -- chemistry
- Bone Marrow Cells -- chemistry
- CD40 Ligand
- Cell Differentiation -- drug effects
- Colforsin -- pharmacology
- Cyclic AMP -- analogs & derivatives
- Cyclic AMP-Dependent Protein Kinases -- metabolism
- Down-Regulation -- drug effects
- Enzyme Inhibitors -- pharmacology
- Flow Cytometry
- Hematopoietic Stem Cells -- chemistry
- Humans
- Ilium -- cytology
- Interleukin-4 -- pharmacology
- Membrane Glycoproteins -- pharmacology
- Myeloid Cell Leukemia Sequence 1 Protein
- Neoplasm Proteins -- biosynthesis
- Neprilysin -- analysis
- Proto-Oncogene Proteins c-bcl-2 -- biosynthesis
- Signal Transduction -- drug effects
- Thionucleotides -- pharmacology
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Publication Type: Journal Article
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