Effects of outer mouth mutations on hERG channel function: a comparison with similar mutations in the Shaker channel. [electronic resource]
Producer: 19990712Description: 3128-40 p. digitalISSN:- 0006-3495
- Amino Acid Sequence
- Animals
- Biophysical Phenomena
- Biophysics
- Cation Transport Proteins
- DNA-Binding Proteins
- Dithiothreitol -- pharmacology
- ERG1 Potassium Channel
- Ether-A-Go-Go Potassium Channels
- Female
- Humans
- Hydrogen Peroxide -- pharmacology
- In Vitro Techniques
- Indicators and Reagents
- Kinetics
- Membrane Potentials
- Models, Biological
- Molecular Sequence Data
- Mutagenesis, Site-Directed
- Oocytes -- metabolism
- Patch-Clamp Techniques
- Point Mutation
- Potassium Channels -- chemistry
- Potassium Channels, Voltage-Gated
- Recombinant Proteins -- chemistry
- Shaker Superfamily of Potassium Channels
- Trans-Activators
- Transcriptional Regulator ERG
- Xenopus laevis
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Publication Type: Comparative Study; Journal Article; Research Support, U.S. Gov't, P.H.S.
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